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A STUDY OF THE CHEMICAL ANALYSES OF THE BLOOD AND URINE, AND OBSERVATIONS ON THE EFFECT OF EXERCISE AND DIET IN THE TREATMENT OF SYPHILIS

CAMERON V. BAILEY, M.D.; ANGUS MacKAY, M.B.

Arch Intern Med. 1920;25(6):628-647.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The treatment of syphilis by injections of arsenobenzol derivatives is, at times, accompanied by more or less grave signs of intoxication. Of these, three distinct types seem to arise. In the first type, symptoms of general malaise shortly follow the administration of the drug and, as a rule, pass off within twenty-four hours. In the second and third types, toxic symptoms may be delayed and not appear until several months after the cessation of treatment. The most pronounced symptoms are associated with the skin or liver.¹ The skin lesion usually develops in the course of the treatment as a maculopapular eruption with considerable thickening. This rapidly becomes generalized. Desquamation is profuse, leaving a thickened, cyanosed and frequently pigmented surface. Pustulation is common. The patient becomes debilitated and has a slight fever. The liver and spleen are frequently enlarged. The urine shows a trace of protein and bile pigment. Patients whose . . . [Full Text PDF of this Article]

Author Affiliations
WOODSTOCK, ONTARIO, CANADA

From the Laboratory of Pathology, Ontario Military (No. 16 Canadian General) Hospital, Orpington, Kent.

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