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A PRELIMINARY REPORT

L. H. NEWBURGH, M.D.; THEODORE L. SQUIER, M.D.

Arch Intern Med. 1920;26(1):38-40.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In studies dealing with the effect of high protein diets on the kidneys of rabbits,¹ it was noted that the animals which ate such diets for a number of months, showed at necropsy widespread arteriosclerosis of the aorta. It was further noted that the extent of the vascular disease was roughly proportional to the duration of the high protein diet.

Thus, the notes from a group of rabbits fed a mixture whose protein content was made high by means of casein² gives the following information in regard to the condition of the aorta:

Rabbit 56: Weight, 2,950 gm.; casein diet three weeks. Aorta normal.

Rabbit 54: Weight, 2,270 gm.; casein diet, two and one-half months. Aorta normal.

Rabbit 61: Weight, 2,500 gm.; casein diet, eleven months. The arch and thoracic portion of the aorta show many raised plaques and streaks.

Rabbit 57: Weight, 1,815 gm.; casein diet one year. The . . . [Full Text PDF of this Article]

Author Affiliations
ANN ARBOR, MICH.

From the Department of Internal Medicine, Medical School, University of Michigan.

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