
I. LIVER REGENERATION FOLLOWING CHLOROFORM INJURY AS INFLUENCED BY THE FEEDING OF CASEIN OR GELATIN
N. C. DAVIS;
G. H. WHIPPLE, M.D.
Arch Intern Med. 1921;27(6):679-687.
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This paper continues the investigation of liver cell repair as influenced by diet factors. Other papers1 show the influence of meat, fat and carbohydrate feeding on the reconstruction of liver cells. It has been pointed out that a uniform central liver necrosis involving half or more of the liver cells can be readily produced by chloroform anesthesia or chloroform injection following a standard fasting period. Under favorable diet conditions this liver necrosis may be completely repaired by the formation of new liver cells in a period of from seven to ten days. The solution or autolysis and removal of the dead liver cells precedes the construction of new liver cells. The construction of this great mass of liver cells is a truly remarkable reaction which is worthy of much study. This speed of growth or reproduction far exceeds the new growth seen in the most malignant neoplasms or even growing
. . . [Full Text PDF of this Article]
Author Affiliations
SAN FRANCISCO
From the George Williams Hooper Foundation for Medical Research, University of California Medical School.
Footnotes
University of California Fellowship.
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