
DERMATITIS AND ALLIED REACTIONS FOLLOWING THE ARSENICAL TREATMENT OF SYPHILIS
JOSEPH EARLE MOORE, M.D.;
ALBERT KEIDEL, M.D.
Arch Intern Med. 1921;27(6):716-747.
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The fact that physicians have frequently failed to appreciate the significance of dermatitis following the arsenical treatment of syphilis, or to differentiate the rashes of minor significance from those indicating grave constitutional disturbances, has prompted us to report the results of our study of a series of such cases of dermatitis and of allied reactions. Our experience has led us to believe that it is possible to divide all untoward reactions of this type into two classes from the viewpoint of their significance with regard to the continuation of arsenic therapy. We also believe that this study throws some light on the etiology, course and prognosis of these toxic phenomena, especially through the recognition of special factors underlying the constitutional disturbances in the graver type of reactions. We have, therefore, reviewed in some detail twenty-three cases of reactions of this group which have occurred within the last six years in
. . . [Full Text PDF of this Article]
Author Affiliations
BALTIMORE
From the Syphilis Department of the Medical Clinic, Johns Hopkins Hospital.
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