This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

J. ALBERT KEY, M.D.

Arch Intern Med. 1921;28(5):511-549.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

INTRODUCTION

It has been suggested (Shipley,¹ Sappington²) that the study of the mitochondria in the erythrocytes in the circulating blood would be of value clinically in estimating the state of activity of the bone marrow.

The term mitochondria was introduced by Benda³ in 1899 to designate certain threadlike granules which he had noted in his studies on spermatogenesis. Many authors had previously described similar protoplasmic granules under various terms. The protoplasmic fila of Flemming⁴ included some poorly fixed mitochondria, and a large percentage of the bioblasts of Altmann⁵ were mitochondria. Cowdry⁶ has carefully reviewed a very extensive literature on the subject and critically examined the descriptions of protoplasmic granules as given by a great many investigators under a very varied terminology. He finds that granules having definite characteristics and hence capable of being separated from other cytoplasmic constituents have been observed and described in the protoplasm of almost every type . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the laboratory of the Department of Medicine of the Harvard Medical School.

Footnotes
This is study No. 9 of a series of studies of the physiology and pathology of the blood from the Harvard Medical School and allied hospitals. This study was made under a grant from the Proctor Fund of Harvard University for the Study of Chronic Diseases.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?