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IV. THE EFFECT OF TOTAL REMOVAL OF THE LIVER AFTER PANCREATECTOMY ON THE BLOOD SUGAR LEVEL

FRANK C. MANN, M.D.; THOMAS B. MAGATH, M.D.

Arch Intern Med. 1923;31(6):797-806.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Previous reported studies¹ on the physiology of the liver have demonstrated that (1) a characteristic group of symptoms followed by death develops after total removal of the liver; (2) these symptoms are associated with decreasing blood sugar, and the various symptoms and death occur at definite blood sugar levels; (3) the injection of glucose after symptoms develop abolishes them and restores the animal to normal, and (4) if glucose is administered after hepatectomy in amounts sufficient to maintain the blood sugar level at normal or above normal, the characteristic symptoms do not develop, but the animal lives for a variable period of time, which is always much longer than if glucose had not been administered, and dies following the development of a totally different group of symptoms.

These striking and very definite results have proved that the maintenace of the normal level of blood sugar is absolutely dependent on the . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, MINN.

From the Division of Experimental Surgery and Pathology, and the Section on Clinical Laboratories, The Mayo Foundation.

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