
THE INDUCTION OF PREMATURE CONTRACTIONS AND AURICULAR FIBRILLATION BY FORCED BREATHINGASSOCIATED WITH A CHANGE IN THE LOCATION OF THE PACEMAKER
FRED M. SMITH, M.D.;
WILLSON B. MOODY, M.D.
Arch Intern Med. 1923;32(2):192-202.
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Numerous attempts have been made to produce premature contractions in the experimental animal by the stimulation of the vagus and the sympathetic nerves. Rothberger and Winterberg1 and Kuré2 were perhaps most successful in these experiments. The former investigators employed combined stimulation of the vagi and the sympathetic, and the latter stimulated the sympathetic. Lewis3 records one instance in which premature beats followed the stimulation of the left vagus on repeated occasions. In a later survey of the subject, Lewis4 questions the interpretation placed by Rothberger and Winterberg on some of their curves, and calls attention to the very low percentage of positive results obtained by Kuré. He further points out that, in the large number of experiments in which he has stimulated the vagus under varying conditions, in only one instance did the extrasystoles seem to be related to nerve impulses. Lewis thus concluded that experimental observations did not demonstrate
. . . [Full Text PDF of this Article]
Author Affiliations
CHICAGO
From the Medical Department of Rush Medical College.
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