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JOHN J. SAMPSON, M.D.

Arch Intern Med. 1924;34(4):490-502.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

INTRODUCTION

Certain constant results have been reported and much interest awakened within recent years in the study of the fragility of erythrocytes. It is not expected that similar findings will prevail in work on leukocytes, which are regarded as approaching more nearly to typical human tissue in structure and function than erythrocytes.

Academically, the observation and measurement of particular reactions of leukocytes as an example of living tissue are of definite interest, but from the clinical standpoint special attention is aroused by the finding of certain reactions by Mauriac, Carbonat and Moureau that are claimed to indicate the prognosis of many diseases.

Mauriac, Carbonat and Moureau¹ have done the primary work of importance in the field of leukocyte fragility. An outline of their work follows:

Mauriac,² in 1916, devised a technic for the determination of the resistance of leukocytes by exposing blood to a hypotonic aqueous solution of 0.206 per . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Medical Services of the Massachusetts General Hospital and the George Williams Hooper Foundation for Medical Research, University of California Medical School.

Footnotes
This paper is No. 34 of a series of papers on the physiology and pathology of the blood from the Harvard Medical School and allied hospitals, a part of the expense of which has been defrayed by a grant from the Proctor Fund for the study of chronic disease.

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