This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

CHARLES W. GREENE, Ph.D.

Arch Intern Med. 1925;35(3):379-388.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Nitrous oxid was discovered by Priestley¹ in 1774, and its anesthetic properties by Sir Humphrey Davy² in 1800. The first attempt to measure the amount of the gas in dog's blood during anesthesia was made by Jolyet and Blanche³ in 1873, a full century after Priestley's discovery. Oliver and Garrett,⁴ 1893, were the first to analyze all the gases of the blood of the dog, comparing the gas distribution before and during nitrous oxid anesthesia. Unfortunately, their results are subject to serious question, and have not been fully confirmed. In the meantime, thousands of nitrous oxid gas anesthesias were performed, and a large body of symptomatic data was developed before the determination of the scientific physiochemical facts on which their explanation rests. The delay was due in no small measure to the difficulties of method.

The ingenious and very workable micro-apparatus of Van Slyke,⁵ 1914, for blood gas analysis has . . . [Full Text PDF of this Article]

Author Affiliations
ASSISTED BY H. M. CURREY, A.M.; F. E. DEXHEIMER, M.D.; E. B. HANAN, A.B., and D. L. HARLAN, A.B. COLUMBIA, MO.

From the department of physiology and pharmacology, laboratory of pharmacology, University of Missouri School of Medicine.

Footnotes
We are indebted to the Committee on Therapeutic Research of the American Medical Association for aid in the purchase of necessary apparatus.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?