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GENEVA A. DALAND, S.B.

Arch Intern Med. 1925;36(6):762-769.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Many studies on the blood of cancer patients have been made in an effort to determine the presence of a specific substance which is characteristic of the disease and which can be detected soon enough to aid early diagnosis. The tests that have been proposed have involved the assumption that the blood of cancer patients was chemically different from that of normal subjects or of those with other diseases, or that a specific cytolysin, enzyme, hemolysin or antibody was present. These tests have proved unsatisfactory either in not being specific for cancer, as has been shown in the study of the phosphorus content of the blood,¹ or as involving so many variable factors as to invalidate them. Underhill and Woodruff² found that an extract of cancer tissue contained a specific substance that was lethal to paramecia. This observation—that there was a substance in cancer tissue different from anything in normal . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the medical service of the Collis P. Huntington Memorial Hospital of Harvard University.

Footnotes
This paper is No. 44 of a series of studies in metabolism from the Harvard Medical School and allied hospitals. The expenses of this investigation have been defrayed, in part, by a grant from the Proctor Fund of the Harvard Medical School for the Study of Chronic Diseases.

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