This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

THE EOSINOPHILIC INDEX AS A GUIDE TO INTRAMUSCULAR INJECTION OF VENOM PROTEIN, WITH CASE REPORT

RALPH H. SPANGLER, M.D.

Arch Intern Med. 1925;36(6):779-787.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Nonspecific desensitization and nonspecific protein therapy have become recognized factors in immunity. Rosenau and Anderson¹ have shown that animals receiving repeated injections of foreign proteins become markedly insusceptible to anaphylactic shock. Longcope² writes: "It seems impossible to avoid the conclusion that in animals sensitized to two proteins anaphylactic shock to the one reduces temporarily the sensitiveness to the second." Dale³ found that a guinea-pig sensitized to several serums and also to egg white could be desensitized to the serum with egg white. Kolmer,⁴ in referring to nonspecific protein therapy, says that "nonspecific activities of bacterial vaccine may exert beneficial and curative effects in disease to which the bacteria incorporated in the vaccine has no etiologic relationship."

CLINICAL REPORTS ON NONSPECIFIC DESENSITIZATION IN ASTHMA

Numerous clinical reports are accumulating which show the beneficial effect of various nonspecific desensitizing agents in asthma as well as in hay-fever, and other sensitization conditions. Miller⁵ . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?