This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

EXPERIMENTAL STUDIES WITH SUGGESTIONS FOR A MORE RATIONAL FORM OF TREATMENT

JACOB A. BARGEN, M.D.; ARCH H. LOGAN, M.D.

Arch Intern Med. 1925;36(6):818-829.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A year ago we believed we had isolated the organism responsible for at least a prominent part in the cause of chronic ulcerative colitis of the so-called idiopathic type.¹

The organism was obtained with sterile swabs through the proctoscope from the depths of an ulcer of the colon, after the latter had been thoroughly cleansed by repeated washings and the top of the ulcer had been carefully wiped with a preliminary swab. Cultures of stools failed to yield the organism but in cultures of the rectal discharge of mucus, pus and blood it was often found as the vastly predominating bacterium. The material obtained was cultured immediately in warm dextrose brain broth,² blood agar and lactose agar and incubated for twenty-four hours. All mediums were titrated to a pH 7.4. The organism isolated in this way as the predominating bacterium and often in pure cultures is a gram-positive, lancet shaped . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, MINN.

From the division of medicine, Mayo Clinic.

Footnotes
Read before the Section on Pharmacology and Therapeutics at the Seventy-Sixth Annual Session of the American Medical Association, Atlantic City, N. J., May, 1925.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?