This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

THEORETICAL AND CLINICAL STUDIES

A. WINKELSTEIN, M.D.

Arch Intern Med. 1926;37(4):541-549.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Despite a tremendous amount of experimental, anatomic and clinical investigation, the problem of the pathogenesis of ulcer is not yet solved. A discussion of the various theories will not be attempted here. Only the general trend of thought will be indicated.

For many years ulcer was considered a local disease. It was thought that the original defect was produced by local causes such as vascular or traumatic lesions and that its chronic character was the result of the unrest and irritation inherent in the stomach. This theory still has many adherents, notably Aschoff.

A study of the recent literature, however, shows a tendency to consider ulcer a local consequence of a general bodily disturbance. For instance, von Bergmann¹ and his pupils, Westphal and Katsch,² following Eppinger and Hess, have found general "vagotonic" stigmas in ulcer patients. Friedman³ has added a "sympathicotonic" group. Peritz and Fleischer⁴ describe a "spasmophilia" of the . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the medical department and the wards for the surgical treatment of diseases of stomach and intestines, Mount Sinai Hospital.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?