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DISEASES OF THE LIVERV. A COMPARATIVE STUDY OF TESTS FOR HEPATIC FUNCTION IN CERTAIN DISEASES OF THE HEMATOPOIETIC SYSTEM
CARL H. GREENE, M.D.;
H. MILTON CONNER, M.D.
Arch Intern Med. 1926;38(2):167-185.
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The recent experiments of Mann, Bollman and Magath1 have shown that a dog will become jaundiced after the complete extirpation of the liver and that the injection of hemoglobin increases the rapidity with which the icterus develops. These observations indicate that the liver must be considered, at least to some extent, as an excretory organ for the bile pigments. The physiologic possibility of a true hemolytic jaundice of extrahepatic origin, a point that heretofore has not met with universal acceptance, must be recognized. The observations of van den Bergh,2 Lepehne,3 McNee,4 Feigl and Querner5 and others on the changes in the van den Bergh reaction in cases of hemolytic jaundice have further served to emphasize the importance of a more accurate knowledge of the activity of the liver.
Jaundice may be produced by three separate pathologic processes: (1) by a mechanical obstruction to the extrahepatic biliary passages with resultant resorption
. . . [Full Text PDF of this Article]
Author Affiliations
ROCHESTER, MINN.
From the Section on Medicine, Mayo Clinic.
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