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WILLIAM G. LENNOX

Arch Intern Med. 1926;38(5):553-565.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Although there have been extensive studies of the metabolism of fasting men and animals, as revealed by examinations of the urine and the expired air, comparatively little has been written concerning alterations in the concentration of various chemical constituents of the blood. During the last three years we have conducted thirty fasting periods in which we have measured various blood constituents. The most striking alteration of the blood was found to be a greatly increased concentration of uric acid. This observation, together with a study of the factors affecting uric acid retention during fasting, has been published.¹ This article deals with observations on the concentration in the blood of nonprotein, urea and amino-acid nitrogen, sugar, cholesterol, fibrin, inorganic phosphorus, total calcium and plasma bicarbonate. Observations concerning chlorides will be presented elsewhere.

MATERIAL AND METHODS

Of the thirty fasting periods, twenty-four were of persons who were fasted as a therapeutic measure . . . [Full Text PDF of this Article]

Author Affiliations
WITH THE ASSISTANCE OF MARIE O'CONNOR AND MARGARET BELLINGER BOSTON

Footnotes
From the laboratory of the department of neuropathology, Harvard Medical School, the medical service of the Massachusetts General Hospital and the Thorndike Memorial Laboratory of the Boston City Hospital. This research was made possible through a grant by the Committee on Epilepsy, New York City. This paper is no. 50 in a series of studies in metabolism from the Harvard Medical School and allied hospitals. The expenses have been defrayed in part by a grant from the Proctor Fund of the Harvard Medical School for the study of chronic diseases.

Fellow in Medicine of the National Research Council during the greater portion of this research.

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