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WITH PREDOMINANT LOCALIZATION IN THE NERVOUS SYSTEM; EARLY DIAGNOSIS AND RADIOTHERAPY

SOLOMON GINSBURG, M.D.

Arch Intern Med. 1927;39(4):571-595.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Nearly a century ago, Hodgkin¹ first described the disease that now bears his name. In his original series of cases—of which five at most were authentic—there was involvement of: (a) the lymph nodes in all cases; (b) the spleen in four cases; (c) the tonsils and the lymphoid tissues of the base of the tongue and pharynx in one case, and (d) the testicle possibly in one case.

In 1859 Wilks² reported one case of Hodgkin's disease in which he noted, in addition, invasion of the liver and kidneys. Six years later,³ he published further observations showing the specific lesions also in the lungs.

In 1865, Cornil and Ranvier,⁴ from a study of the literature and their own cases, had noted that Hodgkin's disease was more than a mere "affection of the absorbent glands and spleen." In addition to involvement of the lymph nodes and spleen, they found the specific . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Surgical and Radiotherapy Departments, Montefiore Hospital.

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