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  Vol. 39 No. 5, MAY 1927 TABLE OF CONTENTS
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STUDIES IN ACROMEGALY

IV. THE BASAL METABOLISM

HARVEY CUSHING, M.D.; LEO M. DAVIDOFF, M.D.

Arch Intern Med. 1927;39(5):673-697.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

CONTENTS

The Metabolic Rate in Acromegaly and Hypopituitarism
Acromegaly and Goiter
The Question Primarily from the Standpoint of the Thyroid
The effect on the metabolism of:
(a) Thyroidectomy
Treatment with Lugol's solution
The Question Primarily from the Standpoint of the Hypophysis
The effect on the metabolism of:
(a) Radiation of the hypophysis
Hypophysectomy

Summary and Conclusions

In a preceding paper in this series by one of us (Davidoff) which deals with the namnesis and symptomatology of acromegaly as recorded in 100 personally observed cases, a brief statement was made concerning the influence of the malady on the basal metabolic rate (B. M. R.1). It is proposed herein to discuss this matter more fully, for it is generally assumed that the thyroid is the organ exclusively concerned in the regulation of tissue combustion.

Many theories have been advanced as to the cause of this condition: Clairmont and von Hoberer's filtration theory; Newaverch and Luebke's microscopic perforation; Lich and Fraenkel's small almost invisible perforation; a rupture subsequently healed, rupture of the interhepatic bile canal of Newaverch, and postperitoneal perforation of the common duct.

One may dismiss from consideration the many and often painstaking studies of . . . [Full Text PDF of this Article]


Author Affiliations

BOSTON


Footnotes

From the Surgical Service of the Peter Bent Brigham Hospital. The preceding papers in this series have been: I. Bailey and Davidoff: Concerning the microscopic structure of the hypophysis cerebri in acromegaly, Am. J. Path. 1, 185-207, 1925. II. Davidoff: Historical Note. III. Davidoff: The Anamnesis and Symptomatology of One Hundred Cases, Endocrinology 10:453, 1926.



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