This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

V. EFFECT OF VARYING DEGREES OF HYDRATION ON SUGAR METABOLISM

EDMUND ANDREWS, M.D.; KARL W. SCHLEGEL

Arch Intern Med. 1927;40(5):637-646.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In a previous communication,¹ it was shown that the relative hydration of the organism had a profound effect on the sugar metabolism. If one-half unit of insulin per kilogram of body weight was injected into dogs in varying degrees of dehydration, the hypoglycemic effect was not only intensified, but it was also materially prolonged. This paper consists of further studies on the subject.

The experiments were repeated on diabetic dogs. We used not only dogs with complete diabetes, but also a dog in which the diabetes was not complete, so that he was able to remain in fairly good health for several months without the use of insulin, except as it was required for the experiments. The blood sugar estimations were made by the micro method of Folin-Wu.²

Chart 1 is a control showing the normal curve of a diabetic animal. The noontide hypoglycemia which has already been studied and . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Surgery, University of Illinois College of Medicine.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?