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RALPH H. MAJOR, M.D.; C. J. WEBER

Arch Intern Med. 1927;40(6):891-899.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In a recent communication¹ we described a method for the determination of guanidine bases in the blood, and noted that certain patients suffering from arterial hypertension showed higher values than did normal persons.

Since this publication, the work has been carried forward and a definite improvement in the method has been achieved. The method differs from that previously described in that the guanidine bases are absorbed by blood charcoal from a filtrate made sligtly alkaline, and subsequently are released from the charcoal by means of acidified alcohol. The details of this method have been described elsewhere,² but a summary of it will be given before discussing the results obtained.

METHOD

(1) Nitroprusside reagent

Stock solution:

10 per cent sodium nitroprusside

10 per cent potassium ferricyanide

10 per cent sodium hydroxide

Author Affiliations
KANSAS CITY, KAN.

From the Department of Internal Medicine, The University of Kansas School of Medicine, Kansas City.

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