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THEIR SELECTIVE ABSORPTION BY THE HYPERPLASTIC THYROID GLAND OF THE DOG

H. B. VAN DYKE, M.D.

Arch Intern Med. 1928;41(5):615-621.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Marine and Feiss¹ and Marine and Rogoff² have demonstrated both by perfusion of the surviving isolated organ and by injections in vivo that the thyroid gland is able to remove iodide iodine from circulating fluids with extreme rapidity. Apparently no one, however, has studied iodine in other forms which are sometimes believed to behave characteristically when administered to persons suffering from disorders of the thyroid gland. The experiments reported in this paper have therefore been undertaken to learn, if possible, to what extent compounds containing iodine other than iodide iodine are selectively absorbed by the thyroid gland.

TECHNIC

In all of the experiments, the selective absorption of the various iodine compounds by the dog's hyperplastic thyroid gland was determined in vivo. When the preliminary experiments were performed about three years ago,³ a large proportion of the animals had suitable goiters. In attempting to complete the work recently, I had great . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Physiological Chemistry and Pharmacology, The University of Chicago.

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