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OBSERVATIONS ON THE BEHAVIOR OF STOMACH AND DUODENUM IN THE PRESENCE OF PAIN

MALCOLM J. WILSON, M.D.

Arch Intern Med. 1928;41(5):633-641.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Various hypotheses have been advanced in explanation of the pain in duodenal ulcer. This pain has been ascribed to irritation of exposed nerve endings in the ulcer base by the acid gastric juice, or to sensitization of the pain-producing mechanism in some way by acid. Bonninger,¹ Palmer² and others hold such views. Mechanical irritation by coarse particles of food is the cause assigned by Pick.³ Spasm of the pyloric sphincter or of the duodenal cap has been put forward by Glaessner and Kreuzfuchs⁴ and many others. Tension, due to an inhibition of relaxation of the pyloric sphincter, combined with strong gastric peristalsis, has been advanced by Hurst⁵ as the cause. That distention of the stomach is an important element in the pain of gastric ulcer and that this pain is readily relieved by passing a tube into the stomach is stated by Poulton.⁶ That the pain is possibly due to . . . [Full Text PDF of this Article]

Author Affiliations
TORONTO

From the Department of Medicine, University of Toronto, and the Medical Service of the Toronto General Hospital.

Footnotes
Thesis submitted for Degree of Doctor of Medicine, University of Toronto. The results of this investigation were presented at the meeting of the American Gastro-Enterological Association, Atlantic City, N. J., May 2, 1927.

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