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AN EXPERIMENTAL COMPARISON WITH THE PHENOLSULPHONPHTHALEIN TEST

ADOLPH BOLLIGER, Ph.D.

Arch Intern Med. 1928;41(5):642-654.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

As reported elsewhere,¹ chronic interstitial nephritis is readily produced in dogs by direct roentgen-ray irradiation of the kidneys. The functional aspect of this experimental disease, as far as the usual tests are concerned, has also been recorded,² and reference has been made to a combined renal function test consisting of the injection of sodium thiosulphate, sodium iodide and phenolsulphonphthalein. The present investigation deals with the excretion of these three substances throughout a course of experimental disease of the kidneys. Subsequently, this combined test was also applied to a large group of normal animals. Observations on normal animals led to an investigation concerning the behavior of normal pregnant animals toward the combined test. The latter are also reported in this paper.

Nyiri³ called attention to the usefulness of sodium thiosulphate as an agent for tests of renal function. He also proposed a combination of the sodium thiosulphate tests with the two . . . [Full Text PDF of this Article]

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From the laboratories of the Henry Ford Hospital.

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