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PANCREATIC FUNCTIONI. THE QUANTITATIVE ESTIMATION OF PANCREATIC SECRETION
SEIZABURO OKADA, M.D.;
EIICHI SAKURAI, M.D.;
TSUNAMOTO IMAZU, M.D.;
KWANICHI KURAMOCHI, M.D.
Arch Intern Med. 1928;42(2):270-281.
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The value of the quantitative estimation of pancreatic function is apparent. Interest in pancreatic function really goes back to the time when Einhorn introduced the duodenal tube.1 Previous to that time, pancreatic functional tests depended on examinations of the feces, which were inaccurate. In these examinations, when many striated muscle fibers, steatorrhea and fatty acid crystals are found, there is generally pronounced dysfunction of the pancreas. Other conditions than pancreatic disease may give positive observations, and often, in distinct pancreatic involvement, the feces tests yield normal reactions, owing to the fact that the enzyme activity of intestinal bacteria has supplanted deficient pancreatic secretion. The Schmidt test,2 Kashiwado's modification3 and Einhorn's bead test4 show also only extreme dysfunction of the pancreas in cases in which the observations are positive. The tests of enzymatic activity in feces as suggested by Gross5 are also more or less inaccurate, probably more often inaccurate than
. . . [Full Text PDF of this Article]
Author Affiliations
TOKYO, JAPAN
From the medical clinic of Prof. R. Inada, Imperial University of Tokyo.
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