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By William G. Lennox, Assistant in Medicine, Harvard Medical School, and Stanley Cobb, Bullard Professor of Neuropathology, Harvard Medical School. Medicine Monographs, Volume XIV. Cloth. Price, $3.50. Pp. 197, with 14 illustrations. Baltimore: Williams & Wilkins Company, 1928.

Arch Intern Med. 1929;43(2):297.

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This is a valuable and fascinating study of the factors involved in convulsions in general. The authors, who have done important investigative work in this field, also prove themselves equipped with a thorough grasp of old and recent research work in physiology, chemistry and pathology which has a bearing on this problem. While cautious in drawing conclusions and not at all ready to offer a solution to the riddle of epilepsy, they lay greater emphasis on chemical factors, such as alkalosis and "oxygen lack," and on disordered sympathetic nerve function and arterial spasm, than on the meager and inconstant information given by microscopic examination. Their reasoning leads them to discard the distinction between "idiopathic" and "symptomatic" epilepsy, as this implies a knowledge which we do not possess. However, they sound this hopeful note: "The encouraging feature is that, although the exact mechanism of seizures is unknown, much can be done . . . [Full Text PDF of this Article]

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