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OPIUM ADDICTIONIV. THE BLOOD OF THE HUMAN ADDICT DURING THE ADMINISTRATION OF MORPHINE
WALTER G. KARR, Ph.D.;
ARTHUR B. LIGHT, M.D.;
EDWARD G. TORRANCE, M.D.
Arch Intern Med. 1929;43(5):684-690.
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In this paper, we present the data obtained from the study of blood drawn from a series of human addicts receiving morphine sulphate hypodermically in sufficient quantity to prevent withdrawal symptoms. All of these addicts exhibited the so-called withdrawal symptoms on cessation of administration of the drug. These symptoms have been described in a previous paper by us1 and are well known to any one familiar with the drug problem. Our purpose in this study has been twofold. The first objective was to search for possible changes in the physicochemical properties of the blood of these addicts; our second, to obtain values in addicts receiving the drug for comparison with the results obtained from the same addicts following the withdrawal of the drug.
EXPERIMENTAL PROCEDURE
During this study the addict received the quantity of drug required, which was administered to him by the nurse in charge of the ward. As
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA
From the Narcotic Wards of the Philadelphia General Hospital.
Footnotes
Submitted for publication, Dec. 27, 1928.
Expenses of this research were defrayed by the Committee on Drug Addictions, New York City. The research was carried out under the guidance of the Philadelphia Committee for the Clinical Study of Opium Addiction in the wards of the Philadelphia General Hospital, which were placed at our disposal through the courtesy of the Director of Public Health, City of Philadelphia.
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