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  Vol. 45 No. 3, March 1930 TABLE OF CONTENTS
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THE RANGE OF EFFECTIVE IODINE DOSAGE IN EXOPHTHALMIC GOITER

II. THE EFFECT ON BASAL METABOLISM OF THE DAILY ADMINISTRATION OF ONE-HALF DROP OF COMPOUND SOLUTION OF IODINE

WILLARD OWEN THOMPSON, M.D.; EDWARD G. THORP, M.D.; PHEBE K. THOMPSON, M.D.; ARCHIBALD C. COHEN, A.B.

Arch Intern Med. 1930;45(3):420-429.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

We have previously shown that during the administration of 1 drop of compound solution of iodine (about 6 mg. of iodine) daily to unselected hospital patients with exophthalmic goiter, there usually occurs as marked a reduction in basal metabolism as during the administration of much larger doses.1 The effect of administering 1/2 drop of the compound solution (about 3 mg. of iodine) daily has now been observed in twenty unselected hospital patients with the disease.

METHOD

The method was the same as that used in the hospital patients who received 6 mg. of iodine daily, except that 1 drop of a 50 per cent compound solution of iodine (roughly, 3 mg. of iodine)2 was administered daily in the metabolism laboratory instead of 1 drop of the undiluted solution.

DATA

The data of the twenty cases are summarized in tables 1 and 2. It may be seen that the average basal . . . [Full Text PDF of this Article]


Author Affiliations

Henry P. Walcott Fellow in Clinical Medicine, Harvard Medical School; BOSTON

From the Metabolism Laboratory and Thyroid Clinic of the Massachusetts General Hospital.


Footnotes

Submitted for publication, Aug. 26, 1929.



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