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THE RANGE OF EFFECTIVE IODINE DOSAGE IN EXOPHTHALMIC GOITERII. THE EFFECT ON BASAL METABOLISM OF THE DAILY ADMINISTRATION OF ONE-HALF DROP OF COMPOUND SOLUTION OF IODINE
WILLARD OWEN THOMPSON, M.D.;
EDWARD G. THORP, M.D.;
PHEBE K. THOMPSON, M.D.;
ARCHIBALD C. COHEN, A.B.
Arch Intern Med. 1930;45(3):420-429.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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We have previously shown that during the administration of 1 drop of compound solution of iodine (about 6 mg. of iodine) daily to unselected hospital patients with exophthalmic goiter, there usually occurs as marked a reduction in basal metabolism as during the administration of much larger doses.1 The effect of administering 1/2 drop of the compound solution (about 3 mg. of iodine) daily has now been observed in twenty unselected hospital patients with the disease.
METHOD
The method was the same as that used in the hospital patients who received 6 mg. of iodine daily, except that 1 drop of a 50 per cent compound solution of iodine (roughly, 3 mg. of iodine)2 was administered daily in the metabolism laboratory instead of 1 drop of the undiluted solution.
DATA
The data of the twenty cases are summarized in tables 1 and 2. It may be seen that the average basal
. . . [Full Text PDF of this Article]
Author Affiliations
Henry P. Walcott Fellow in Clinical Medicine, Harvard Medical School; BOSTON
From the Metabolism Laboratory and Thyroid Clinic of the Massachusetts General Hospital.
Footnotes
Submitted for publication, Aug. 26, 1929.
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