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V. THE SECRETORY MECHANISM OF DIGESTIVE JUICES

SEIZABURO OKADA, M.D.; KWANICHI KURAMOCHI, M.D.; TOSHIO TSUKAHARA, M.D.; TATSUO OOINOUE, M.D.

Arch Intern Med. 1930;45(5):783-813.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the foregoing paper¹ we noted that hypoglycemia provokes the gastric, pancreatic and biliary secretions, and that hyperglycemia inhibits these. Since hypoglycemia induces humorally an excitatory impulse and hyperglycemia an inhibitory impulse to the secretory center, since from this center the stimulus and the inhibitory impulse are transmitted through the autonomic nervous system to the acting tissue cells, and since this phenomenon plays an important rôle as a regulatory mechanism in the process of gastric, pancreatic and biliary secretion, we called this phenomenon the "humoroneural regulation of the secretion of digestive juices." It is proved that the salivary secretion is excepted from this regulation. Furthermore, in dogs provided with a Thiry-Vella fistula, the secretion of the intestinal juice does not show this regulatory mechanism. It is well known that the alimentary hyperglycemia is usually due to the increase of dextrose in the blood. Therefore it is of interest to know . . . [Full Text PDF of this Article]

Author Affiliations
TOKYO, JAPAN

From the Medical Clinic of Prof. R. Inada, Imperial University of Tokyo.

Footnotes
Submitted for publication, Oct. 4, 1929.

This and the foregoing papers refer not only to the pancreatic function but also to the secretory functions of the whole glands of the digestive tracts, so that the title "Pancreatic Function" does not cover the whole contents of the researches. Still we feel it rather fair to keep this title to show the origin of these works.

Preliminary reports were: Studies on the Mechanism of the Secretion of Digestive Juices (in Japanese) Nippon Naikagakkai Zasshi 17:106 (May 10), 1929; abst. in English, ibid., June 10, 1929; The Humoroneural Regulation of the Secretions of the Digestive Organs: II. Report, Proc. Imperial Acad. Tokyo 6:18 (Jan.) 1930.

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