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II. NITROGEN METABOLISM

A. MAURICE WAKEMAN; CLARE A. MORRELL

Arch Intern Med. 1930;46(3):382-401.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In the preceding paper,¹ determinations of nonprotein nitrogen and its individual nitrogenous components in the blood of normal Macacus rhesus monkeys and similar animals infected with yellow fever were presented. It was shown that in the terminal stage of yellow fever, the amino-acid nitrogen in the blood increased greatly, both in absolute magnitude and in proportion to total nonprotein nitrogen and other individual nitrogenous constituents. Urea nitrogen, on the other hand, did not rise, or rose little in proportion to amino-acid and total nonprotein nitrogen. In a few instances it actually diminished. The nature of the observed changes indicates that the chief disturbance of nitrogenous metabolism in yellow fever is the destruction or impairment of the power of the liver to deaminize amino-acids and to form urea.

However, definite conclusions cannot be drawn from studies of the blood alone. In order to estimate the rates of formation and destruction of . . . [Full Text PDF of this Article]

Author Affiliations
NEW HAVEN, CONN.

Footnotes
Submitted for publication, Jan. 30, 1930.

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