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REPORT OF NINE CASES

DOUGLAS H. SPRUNT, M.D.

Arch Intern Med. 1930;46(3):494-501.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Merbaphen (novasurol) is accepted as a useful diuretic in many cases of edema due to congestive heart failure. Attention has been called by Marvin¹ and others to its immediate toxic effect in some cases. That there may be damage to the renal epithelium for as long as four weeks after the last injection of merbaphen was mentioned by Redlich.² He reported an instance of damage to the tubular epithelium of the kidney in a patient with tuberculosis who died four weeks after an injection of 1 cc. of the drug. Saxl³ immediately claimed that the damage to the kidney could not have been due to the merbaphen because of the period of time that had elapsed since its use. He said, moreover, that even if the mercury were responsible for the lesions, it was given under conditions that clearly contraindicated its use. The question of the toxicity of merbaphen raised . . . [Full Text PDF of this Article]

Author Affiliations
NEW HAVEN, CONN.

From the Department of Pathology, Yale University School of Medicine.

Footnotes
Submitted for publication, Feb. 28, 1930.

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