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MORRIS GOODMAN, M.D.; JOSEPH E. CONNERY, M.D.

Arch Intern Med. 1930;46(6):1018-1025.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Widal, Abrami and Iancovesco¹ described a test for liver dysfunction which they believe is based on an anaphylactic blood reaction. This reaction, to which they gave the name of hemoclastic crisis, manifests itself as (a) leukopenia with a relative lymphocytosis, (b) fall of blood pressure, (c) decrease in the refractometric index of the serum and (d) an increase in the coagulation time of the blood. The authors stated that these phenomena are a response of the presence of low proteins (peptones) in the general circulation. Their theory for the appearance of these products in the general circulation is that during digestion of protein the partially digested proteins which reach the liver via the portal circulation pass through and enter the general circulation when the liver is diseased. The normal liver prevents this transmission, because it has the property of arresting the low proteins (proteopexic function).

These authors offered the following . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Medicine, New York University and Third Medical Division, Bellevue Hospital.

Footnotes
Submitted for publication, Feb. 14, 1930.

The tests for liver function were carried out by Dr. Norman Jolliffe as a part of his study of liver function (J. Clin. Investigation 8:419 [April] 1929).

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