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S. J. COHEN, M.D.; M. J. MATZNER, Ch.E., M.D.; IRVING GRAY, M.D.

Arch Intern Med. 1930;46(6):979-983.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

During the past year we were able to demonstrate the presence of injected neutral red in the gastric extractions of three patients who had pernicious anemia. These determinations prompted us to make this report.

The use of neutral red has been advocated in the study of the gastric secretory function. Fuld¹ discovered that neutral red would appear in a Pavlov pouch after the dye was placed in the large stomach. Several years later, Finkelstein² found that it was practically the only dyestuff eliminated in appreciable quantities in the Pavlov pouches of dogs after intramuscular administration. One year later, Glaessner and Wittgenstein³ applied this fact clinically.

Davidson, Willcox and Haagensen⁴ concluded that neutral red was excreted in achylia accompanying every condition except pernicious anemia. In their studies, they investigated eight cases of pernicious anemia, and did not recover neutral red in the gastric extractions after two hours. Their statement that the . . . [Full Text PDF of this Article]

Author Affiliations
BROOKLYN

From the medical service of Dr. Meyer Rabinowitz, Gastro-Intestinal service of Dr. Irving Gray and the Department of Pathology, Jewish Hospital of Brooklyn.

Footnotes
Submitted for publication, April 21, 1930.

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