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FRED M. SMITH, M.D.; GEORGE H. MILLER, M.D.

Arch Intern Med. 1930;46(6):988-993.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The present investigation was suggested by the study of the gastric manifestations associated with an irritable colon.¹ The epigastric distress was demonstrated to be gastric in origin. It is intensified by an aggravation of the bowel symptoms, and may be induced by a distention of the colon. In the roentgen examination of the gastro-intestinal tract, a pyloric spasm was the most prominent observation. There was also frequently an increase in the peristaltic action of the stomach. These observations were not constant and varied in different persons, but they were more evident during periods of apparent increased tension in the colon. These observations suggested that an alteration in the tone, particularly in the pyloric region and in the peristaltic action, was responsible for the epigastric distress, and that the latter was induced by a stimulation from the colon.

Clinical and roentgen observations² have strongly supported the theory of a reflex stimulation . . . [Full Text PDF of this Article]

Author Affiliations
IOWA CITY

From the Department of Internal Medicine, State University of Iowa.

Footnotes
Submitted for publication, May 28, 1930.

Presented in part before the Society of Clinical Investigation at Atlantic City, May 6, 1929, and before the International Physiological Congress, Boston, Aug. 20, 1929.

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