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I. GOLDSTEIN'S HEREDOFAMILIAL ANGIOMATOSIS WITH RECURRING FAMILIAL HEMORRHAGES (RENDU-OSLER-WEBER'S DISEASE)
HYMAN I. GOLDSTEIN, M.D.
Arch Intern Med. 1931;48(5 I):836-865.
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In the opening paragraph of his paper on "Gastric Hemorrhage Due to Familial Telangiectasis," Boston1 stated:
A cursory survey of the literature disclosed records of 3 cases of recurrent rectal hemorrhage, one of oral bleeding and one of hematemesis which had been accompanied by cutaneous telangiectases. Wilson gave us the first recorded instance of rectal bleeding from telangiectases in 1896; Fox recorded a case in 1908; Phillips in 1908 cites the case of an extensive telangiectasis of the skin and mucous surface of the mouth with hemorrhages from the pharynx, and possibly from the stomach. Hutchison and Oliver's patient experienced recurrent rectal hemorrhage; and Pringle in describing his case alludes to recurrent attacks of vomiting blood.
Boston stated further that telangiectasia has not been considered in connection with painless hemorrhage of either gastric or rectal origin, and that the familial etiologic nature of the disease is evidenced in the
. . . [Full Text PDF of this Article]
Author Affiliations
CAMDEN, N. J.
Footnotes
Submitted for publication, Jan. 3, 1931.
A second paper on this subject with clinical reports of my cases will be published later.
This subject was discussed by me with lantern demonstration before the Prof. L. A. Nekám Dermatologic Clinic and the Prof. Baron A. Korányi Medical Clinic, Royal University, Budapest, Hungary; before the Hungarian Dermatological Society in October, 1931, at Budapest; before the American Medical Association of Vienna, in October, 1931, and before a group of visiting physicians and medical staff of the Prof. Paul Morawitz Medical Clinic, Leipzig University, Leipzig, Germany (1931).
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