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C. W. LUEDERS, M.D.; M. E. WATSON, B.S.

Arch Intern Med. 1932;49(2):330-342.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The present study was undertaken to discover whether insulin therapy, when applied to nondiabetic patients with malnutrition promotes the normal secretion of pancreatic enzymes and to prove thereby that the striking gains in weight in such a group may be attributed in part to an increased digestion and assimilation of aliment. Other investigators¹ have shown that the ingestion of the same diet without insulin produced comparatively slight increase in weight. In the recent literature on carbohydrate metabolism,² physiologists accept the fact that the hypoglycemia produced by the injection of insulin, and acting on the secretory and motor centers in the medulla, causes gastric and intestinal hypermotility, as well as pancreatic and biliary hypersecretion. The effect of the injection of insulin in augmenting the normal function of the tissues to hold water, carbohydrate, fat and protein is the fundamental criterion of insulin therapy and will be mentioned later in . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Gastro-Intestinal Clinic, Out-Patient Department, Pennsylvania Hospital.

Footnotes
Submitted for publication, July 28, 1931.

Read before the Thirty-Fourth Annual Meeting of the American Gastro-Enterological Association, Atlantic City, May 5, 1931.

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