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LEO M. ZIMMERMAN, M.D.

Arch Intern Med. 1932;49(3):409-420.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

During the period, about forty years ago, when Minkowski¹ was establishing a probable relationship between the pancreas and diabetes, two Italian workers, de Renzi and Reale,² reported diabetes in dogs following the extirpation of the salivary glands and of the duodenum. Minkowski felt that the removal of the duodenum could not be effected without at the same time materially damaging the pancreas. He repeated the experiments on the salivary glands and found a mild (from 1 to 3 per cent), inconstant, transient glycosuria after removal of these glands. He concluded that this glycosuria was nonspecific, that it was incidental to the operation or the anesthetic, and that the salivary glands had nothing to do with the control of the sugar metabolism. This is the view that, with very few exceptions, has prevailed regarding the function of the salivary glands.

In 1907, Ferrannini³ reported a case of "salivary . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Metabolic Laboratory, Department of Physiology, Nelson Morris Institute for Medical Research, Michael Reese Hospital.

Footnotes
Submitted for publication, June 24, 1931.

This work was aided by a grant from the Max Pam Fund for Metabolic Research.

Associate in Surgery, Northwestern University Medical School.

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