This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

WITH SPECIAL REFERENCE TO CLASSIFICATION AND BENIGN TYPES

GEORGE M. PIERSOL, M.D.; EDWARD STEINFIELD, M.D.

Arch Intern Med. 1932;49(4):578-588.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The syndrome first described by Schultz¹ as agranulocytosis was considered by him to represent a definite clinical entity. Other observers who also held this view based their opinions on the fairly uniform clinical history, particularly the age and sex predilection and the peculiarity in the distribution of the supposedly specific lesions. However, subsequent contributions have indicated that a similar hematologic picture occurs with varying clinical features and apparently is based on a variety of causes. Later observations have strengthened the view that the disease is symptomatic of a number of etiologic factors, such as infection, chemical agents and the action of x-rays and radium. The protagonists of the theory that the disease is a distinct entity believe: (1) that it represents a specific primary disease or infection of the granulopoietic structure in the bone marrow with the necrotic lesions in the mouth as an expression (Schultz), or (2) that . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Graduate School of Medicine, University of Pennsylvania, and the Laboratories of the Jewish Hospital.

Footnotes
Submitted for publication, July 3, 1931.

Read before the Association of American Physicians, Atlantic City, N. J., May 6, 1931.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?