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A. B. STOCKTON, M.D.

Arch Intern Med. 1932;50(1):142-149.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The efficiency of sodium bismuth tartrate as a clinical diuretic and antiedemic has been sufficiently demonstrated in previous studies.¹ It appeared desirable to throw light, if possible, on the mechanism of these actions. It was especially desired to ascertain if the tissues in general might be the seat of the bismuth action. This was tried by attempts to correlate the changes in the metabolites, especially the chlorides of the blood and urine, with the diuretic action. Such an attempt on healthy rabbits indicated a tissue action of the bismuth.² The same was found to be true not only for bismuth, but also for theophylline, and possibly digitalis, in human subjects discussed in a preliminary report.³ This paper presents various data and details of the results in patients with and without edema receiving bismuth.

METHODS

The results with bismuth were obtained in a total of fifteen different patients . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

From the Departments of Pharmacology and Medicine, Stanford University School of Medicine.

Footnotes
Supported, in part, by a grant from the Rockefeller Fluid Research Fund of the School of Medicine, Stanford University.

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