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INFLUENCE ON CARBOHYDRATE METABOLISM OF EXPERIMENTALLY INDUCED HEPATIC CHANGESI. FASTING AND ADMINISTRATION OF THYROXINE
L. ALTHAUSEN, M.D.;
Dr. med. E THOENES
Arch Intern Med. 1932;50(1):46-57.
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This experimental study was undertaken in an attempt to gain more information on certain disturbances of carbohydrate metabolism previously noted in patients with diseases of the liver.1 The outstanding abnormality was on insufficiency of the blood sugar-regulating mechanism of the liver revealed by a modification of the dextrose tolerance test. Following the injection of 20 units of insulin and the oral administration of 50 Gm. of dextrose in 1,500 cc. of water, normal persons were found to have a blood sugar curve that differed little from that obtained after the administration of 50 Gm. of dextrose alone. On the other hand, patients with hepatic disease after this test usually showed an initial rise of the blood sugar, which often exceeded the normal, and which was followed by an abrupt decline. In some cases there was no initial rise, but an uninterrupted diminution of the blood sugar level. Both types
. . . [Full Text PDF of this Article]
Author Affiliations
SAN FRANCISCO; LEIPZIG, GERMANY
From the Medizinische Universitätsklinik, Leipzig, Prof. Dr. Morawitz, Director.
Footnotes
Fellow of the J. Simon Guggenheim Memorial Foundation, from the Department of Medicine, University of California Medical School.
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