This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

EVALUATION OF THE RÔLE OF DUODENAL REGURGITATION IN THE CONTROL OF GASTRIC ACIDITY IN MAN (BOLDYREFF THEORY)

HARRY SHAY, M.D.; ALBERT B. KATZ, M.D.; EUGENE M. SCHLOSS, M.D.

Arch Intern Med. 1932;50(4):605-620.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Since Heidenhain's¹ observation that the pure gastric juice in the normal dog was secreted at an acidity of 0.5 to 0.6 per cent hydrochloric acid, and particularly since its confirmation in human beings by Carlson,² physiologists have puzzled over the mechanism involved in the reduction of this high acidity to the one ordinarily seen in gastric contents. In general, the many theories evolved to explain the reduction concern themselves with one or the other of two mechanisms: (1) neutralization and (2) dilution. Babkin³ recently gave an excellent résumé of this subject. It is our intention to inquire into only one of these theories, the one that has doubtless enjoyed the greatest popularity. This is the theory developed by Boldyreff and styled by him "the self-regulation of gastric acidity." Briefly, it contends that the small intestine cannot tolerate an acid stronger than from 0.1 to 0.15 per cent . . . [Full Text PDF of this Article]

Author Affiliations
PHILADELPHIA

From the Gastro-Intestinal Clinic of the Jewish Hospital, Philadelphia.

Footnotes
Read before the Physiological Society, University of Pennsylvania, Jan. 11, 1932.

Presented in abstract before the Section of Medicine, College of Physicians, Philadelphia, Dec. 28, 1931.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?