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JOHN W. SHIRER, M.D.; WALLACE DUNCAN, M.D.; RUSSELL L. HADEN, M.D.

Arch Intern Med. 1932;50(6):829-835.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Elevation of the serum protein content, except in dehydration, is observed rarely in clinical practice. Even with marked loss of fluid from the body the increase of protein in the blood usually is not great. True hyperproteinemia is exceedingly rare. Loeper, Forestier and Tonnet¹ found the serum protein to be 11 mg. per hundred cubic centimeters in one case of malignant tumor of the kidney. Wu² reported that one patient with kala-azar had a serum protein of 10.52 mg. and a serum globulin of 9.06 mg. The highest serum protein content observed by Rowe³ was 10.4 mg. in a patient suffering from glandular enlargement. However, no known clinical syndrome shows constantly an increase in the protein of the blood.

Few studies on proteins of the blood in patients with multiple myelomas have been reported. Ellinger⁴ demonstrated qualitatively the presence of Bence-Jones protein in blood and in . . . [Full Text PDF of this Article]

Author Affiliations
CLEVELAND

From the Cleveland Clinic.

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