This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

COMPARISON OF THEIR EFFECTS WHEN ADMINISTERED ORALLY WITH THE EFFECT OF THYROXINE INJECTED INTRAVENOUSLY IN AN ALKALINE SOLUTION

WILLARD O. THOMPSON, M.D.; PHEBE K. THOMPSON, M.D.; LOIS F. N. DICKIE, B.M.

Arch Intern Med. 1933;52(4):576-592.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1926 we gave some Squibb's thyroxine for oral use to two patients with low basal metabolism for a few days in doses of from 2 to 10 mg. daily and, having observed no effect, were content to conclude that the current opinion about its lack of effect when administered by mouth was correct. However, as time went on, it seemed worth while to give the matter more serious study.

A review of the literature reveals some difference of opinion as to whether or not thyroxine is effective when administered by mouth. Swingle, Helff and Zwemer,¹ by observing the weight and pulse rate, Burmeister,² by observing the weight and urinary output, and Abelin,³ Schneider,⁴ and Boller and Högler⁵ (Schering's thyroxine), on the basis of determinations of basal metabolism, concluded that thyroxine is virtually without effect when administered by mouth to normal human beings. Weiss⁶ observed no effect in some cases . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Medicine, Rush Medical College and the Presbyterian Hospital.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?