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  Vol. 52 No. 4, OCTOBER 1933 TABLE OF CONTENTS
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BENIGN FAMILIAL POLYCYTHEMIA

ANTHONY SPODARO, M.D.; CLAUDE E. FORKNER, M.D.

Arch Intern Med. 1933;52(4):593-602.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Few instances of familial polycythemia have been reported. No thorough studies have been made of the families of patients with this condition.

Nichamin,1 in 1907, observed a patient with mild polycythemia whose mother and sister had enlargement of the spleen and cyanosis. No studies were made on the blood of the relatives.

Bernstein,2 in 1914, recorded what he believed to be the first published report of the familial incidence of polycythemia. The blood of the patient contained 12,500,000 red corpuscles per cubic millimeter and 140 per cent hemoglobin. There were splenomegally and cyanosis. The son of this patient did not have a palpable spleen, but his blood showed 7,500,000 red corpuscles and 120 per cent hemoglobin.

Tancré,3 in 1917, reported the occurrence of polycythemia in two sisters, one of whom had 13,000,000, and the other 6,100,000, red blood corpuscles per cubic millimeter of blood. He suggested the . . . [Full Text PDF of this Article]


Author Affiliations

BOSTON

From the Thorndike Memorial Laboratory, the Second and Fourth Medical Services (Harvard), Boston City Hospital, and the Department of Medicine of the Harvard Medical School.



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