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IV. RETENTION OF UREA IN THE NEPHROSIS SYNDROME

G. P. GRABFIELD, M.D.

Arch Intern Med. 1933;52(4):632-636.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It has previously been noted by Peters and others¹ that patients exhibiting the nephrosis syndrome retain a large proportion of the intake of nitrogen without an increase in the nonprotein nitrogen in the blood, and that even when crystalline urea is added to the diet, it is retained. Peters and Van Slyke² thought that the retention of nitrogen serves to make up the loss of body protein chiefly in the form of albumin excreted in the urine. If this is true, it accounts in part for the retention of sulphur noted formerly.³ So far as I have been able to ascertain, no studies have been made on the relation between the excretion of nitrogen and that of sulphur in this condition when crystalline urea has been added to a diet already high in protein. I shall report metabolism studies on a patient, whose case history was included . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Medical Clinic of the Peter Bent Brigham Hospital.

Footnotes
This work was done under a grant from the Proctor Fund for the Study of Chronic Diseases of Harvard University.

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