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THEIR RESPONSE TO CERTAIN TYPES OF THERAPY

WILLIAM P. MURPHY, M.D.

Arch Intern Med. 1933;52(6):829-838.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The magnitude of the rise in reticulocytes following the institution of therapy has been quite generally accepted as a means of evaluating the potency of various substances used in the treatment for pernicious anemia. The rate of the reticulocyte response and subsequent return to a normal level may also indicate the efficiency of the therapeutic substance used.

The magnitude of the response of the reticulocytes will depend to some extent on the method of staining and the technic employed in counting the cells, on the initial erythrocyte count at the time treatment is instituted, on the presence of complicating disease conditions and perhaps on the age of the patient. If these factors are given due consideration, the form and magnitude of the reticulocyte curve serve as a rough index of the potency of various substances used, particularly if treatment is carried out perorally in the usual manner and the amount . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Medical Clinic of the Peter Bent Brigham Hospital.

Footnotes
Read before the Association of American Physicians, Washington, D. C., May 11, 1933.

This study was aided by a grant from the DeLamar Mobile Research Fund of Harvard University.

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