This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

WESLEY W. SPINK, M.D.

Arch Intern Med. 1934;54(5):805-817.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Little is known concerning the function of the eosinophil white blood cell. Its origin and life cycle are still a matter of controversy. In man, the eosinophil normally constitutes from 1 to 4 per cent of the circulating leukocytes, and an increase is of diagnostic value in several diseases. However, it is well known that normal guinea-pigs may have as many as 30 per cent eosinophils. Brown¹ first recognized the diagnostic importance of eosinophilia in trichinosis. He recognized, however, that in severe infections the circulating eosinophils may be either absent or few.

Opie² produced in normal guinea-pigs with marked eosinophilia, infections with Bacillus tuberculosis, Bacillus pyocyaneus, Bacillus mucosus-capsulatus and Streptococcus pyogenes. During the course of the infection, the eosinophils disappeared not only from the blood but from the tissues. Coincident with their disappearance from the blood, there was an accumulation of eosinophils near the site of inoculation. Canon . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Department of Comparative Pathology, Harvard Medical School, Second and Fourth Medical Services (Harvard) and the Thorndike Memorial Laboratory, Boston City Hospital.

Footnotes
This work was made possible by a grant from the William W. Wellington Memorial Research Fund of Harvard Medical School.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?