This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

COMPARISON OF CALORIGENIC EFFECTS WITH THOSE OF MONOSODIUM THYROXINE AND THYROXINE IN ALKALINE SOLUTION

WILLARD O. THOMPSON, M.D.; PHEBE K. THOMPSON, M.D.; SAMUEL G. TAYLOR III, M.D.; LOIS F. N. DICKIE, B.S.

Arch Intern Med. 1934;54(5):818-828.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

We have shown that single large doses of thyroxine in alkaline solution have about 63 per cent as much effect when administered by mouth as when given intravenously.¹ However, the oral administration of the monosodium salt in tablet form produces only about 25 per cent as much effect as the intravenous administration of thyroxine in alkaline solution, when the comparison is made on the basis of the daily doses of the two substances required for maintenance of the basal metabolism of patients with myxedema at the normal level.² As a continuation of our study of the calorigenic action of various forms of thyroxine we have now determined the effects of administering single large doses of pure thyroxine both by mouth and directly into the duodenum, and have compared them with the effects of oral administration of single large doses of monosodium thyroxine in tablet form and of thyroxine . . . [Full Text PDF of this Article]

Author Affiliations
Resident in Medicine, Cook County Hospital; CHICAGO

From the Department of Medicine, Rush Medical College, and the Presbyterian and Cook County hospitals.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?