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PERNICIOUS ANEMIARESULTS OF TREATMENT OF THE NEUROLOGIC COMPLICATIONS
ROY R. GRINKER, M.D.;
ERNESTINE KANDEL, M.D.
Arch Intern Med. 1934;54(6):851-871.
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The introduction of liver for the treatment of pernicious anemia by Minot and Murphy has provided an efficacious method of increasing the number of red blood cells and the percentage of hemoglobin to figures approaching normal, thereby relieving the general asthenic symptoms and prolonging the lives of patients indefinitely. The effect of liver on the neurologic complications of pernicious anemia also has been studied with great interest, but with the use of less certain criteria on which conclusions may be based. The literature already contains reports of several studies carried out over long periods of time which seem to indicate both prophylactic and curative values of liver extracts on the neurologic complications. However, some clinicians attributed an indirect action to the liver and suggested that the usual gain in general strength enhances the patient's powers of compensation for his neurologic defects, while others denied any noteworthy change in the nervous
. . . [Full Text PDF of this Article]
Author Affiliations
CHICAGO
From the Division of Neurology and Neurosurgery and the Department of Medicine of the University of Chicago.
Footnotes
Douglas Smith Fellow.
Aided by a grant from the Josiah Macy Jr. Foundation.
Read before the Section on Nervous and Mental Diseases at the Eighty-Fourth Annual Session of the American Medical Association, Milwaukee, June 15, 1933.
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