This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

CAMILLE MERMOD, M.D.; W. DOCK, M.D.

Arch Intern Med. 1935;55(1):52-60.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The experimental observations reported here were designed to give additional information as to the relative ability of the reticulocytes to withstand such hemolytic substances as saponin in the living animal and in shed blood and to determine the rate and extent to which they mature into nonreticulated cells. These points were considered of importance in connection with the validity of the two current theories as to the origin of macrocytic hyperchromic (addisonian or pernicious) anemias. The maturation theory ascribes the disease to the absence of sufficient quantities of a substance needed for the maturation and release of the red cells; the hemolytic theory ascribes the disease to the action of an absorbed hemolytic agent. Since neither theory is adequately proved, it seemed desirable to know more about the properties of the curious vital-staining cells, the sudden increase of which, in spontaneous and induced remissions of macrocytic anemia, is such a . . . [Full Text PDF of this Article]

Author Affiliations
SAN FRANCISCO

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?