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REPORT OF A CASE WITH PARTIAL AUTOPSY

ROBERT B. HAINING, M.D.; THEODORE S. KIMBALL, M.D.; OSMONDE W. JANES, M.D.

Arch Intern Med. 1935;55(4):574-591.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Thirty years ago acute leukemia was regarded as a disease of but one type—lymphatic leukemia. Gradually myelogenous acute leukemia came to be recognized, which seems to occur far more frequently than the lymphatic variety. Today room is being made for a third claimant —monocytic leukemia.

Full acceptance of monocytic leukemia as a clinical and pathologic entity will depend ultimately on indisputable proof of the derivation of the circulating monocytes. Such proof will involve the recognition of a third hematopoietic system, the occasional hyperplasia of which may logically be expected to result in leukemia comparable to myeloid and lymphoid leukemia. Unfortunately, the ancestry of cells, like the ancestry of human beings, is often easy and pleasing to claim but hard to verify. The studies of Maximow,¹ of Kiyono² and of Sabin³ have convinced most investigators that circulating monocytes are derived from some part of the reticulo-endothelial system. Exactly . . . [Full Text PDF of this Article]

Author Affiliations
LOS ANGELES; GLENDALE, CALIF.

From the Department of Pathology, Los Angeles County Hospital; the Division of Medicine, College of Medical Evangelists, and the Glendale Sanitarium and Hospital.

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