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JACOB MEYER, M.D.; LOUIS SCHEMAN, M.D.; H. NECHELES, M.D., Ph.D.

Arch Intern Med. 1935;56(1):88-97.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

While conducting experiments on the mechanism of pain in peptic ulcer it occurred to one of us to try the effect of essential oils. Oil of peppermint was selected because it is known as a household remedy for relieving gastric distress. This paper is a report of the action of oil of peppermint on the motility and secretion of the stomach of patients with peptic ulcer.

The "Pentsao Kang Mu" (Li Shih Chen, 1597 A. D.),¹ in which is summarized the oldest knowledge of Chinese medicine, records the use of oil of peppermint as an antispasmodic. According to Heupke,² peppermint as a remedy was mentioned at the time of Charlemagne.

Wallace and Jackson³ found that oil of peppermint in the intestine influences gastric secretion by reflex action. Meyer and Gottlieb in their textbook⁴ stated that carminatives increase the muscular activity of the alimentary canal. Muirhead and . . . [Full Text PDF of this Article]

Author Affiliations
CHICAGO

From the Department of Gastro-Intestinal Physiology and the Stomach Study Group, Nelson Morris Institute of the Michael Reese Hospital.

Footnotes
The study was carried on by the aid of a grant from the Louis L. Cohn and Kuppenheimer Funds to the Stomach Group of the Michael Reese Hospital.

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